MKI67 and neoplasm: In addition, the histological evaluation of tumor slices after 24 h PMNSG plus 1064 nm laser treatment for the hematoxylin-eosin (H&E), Ki-67 and terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling (TUNEL) staining showed most significant tumor tissue damage, proliferation inhibition and cell apoptosis extent, respectively (Fig. 6h).