PKCδ itself becomes phosphorylated at tyrosine residue 311 (Tyr 311) and PKCδ phosphorylation has been shown to be required for NLRC4 phosphorylation and NLRC4 inflammasome activation in BMDMs in response to infection with Salmonella Typhimurium72, but the identity of the tyrosine kinase responsible for PKCδ phosphorylation has remained unknown for nearly a decade. This evidence concerns the gene PRKCD and infection.