MYCN and neuroblastoma: Then, the authors tried to match the features of normal developmental cell populations to those of the NB risk subgroups defined by genetic alterations: MYCN-amplified high-risk tumors, MYCN-nonamplified high-risk tumors (TERT-rearranged or harboring telomere lengthening), and intermediate/low-risk tumors (lacking telomere maintenance) [9, 20, 78].