LRRK2 and Parkinson disease: Variants of genes such as SNCA (encoding α-Synuclein (α-Syn), including the A53T mutation), GBA (glucosylceramidase β, encoding GBA protein), LRRK2 (leucine-rich repeated kinase 2, encoding LRRK2 protein) and MAPT (encoding microtubule associated protein Tau) have been found to raise the possibility of PD onset [108].