The release of inflammatory cytokines such as TNF-α, IL-1β, IL-6, and IL-8, and the production of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), can lead to cardiac hypertrophy and impaired cardiac function [31,32,33,34]. Here, CXCL8 is linked to cardiac hypertrophy.