As an example, virgin coconut oil (VOC), mainly composed of medium chain saturated fatty acids (6–12 carbons), reduced IL-1β protein, caspase-1, and NLRP3 genes expression at different doses in AD (receiving Amyloid-β) and in high-fat diet (HFD) models both in vitro and in vivo [101]. The gene discussed is NLRP3; the disease is Alzheimer disease.