Moreover, females with the GG genotype of PER2 rs2304672 in the VLFC had significantly higher risks of obesity and abdominal obesity compared with the references (OR: 1.49, 95% CI:1.18–1.87, p = 0.0007; OR: 1.85, 95% CI 1.35–2.54, p = 0.0001 respectively), whereas no differences were detected in minor C allele carriers. The gene discussed is PER2; the disease is obesity due to melanocortin 4 receptor deficiency.