CNR1 and cancer: While proving that CB1 expression increased following Quercetin administration, the incomplete inhibition of the effects observed from combined administration of CB1 antagonist SR141716 seems to be a critical point of the study; if CB1 upregulation and Quercetin’s effects on cancer cell proliferation and apoptosis were entirely due to a direct Quercetin–CB1 interaction, the administration of an antagonist should have reverted the effects completely and not only partially.