For example, albumin is part of the NAFLD Fibrosis Score along with age, fasting glucose, BMI, platelets, and AST/ALT, which has a sensitivity of 43% and a specificity of 96% for detecting liver fibrosis; Haptoglobin, ApoA1 and a2-macroglobulin are some of the components of Fibrotest (sensitivity: 92%, specificity: 71%); a2-macroglobulin is part of the Hepascore (sensitivity: 75%, specificity: 84%); and albumin and globulin together with other clinical and laboratory parameters achieved 57% sensitivity and 90% specificity in an adult model with NAFLD and diabetes. This evidence concerns the gene ALB and metabolic dysfunction-associated steatotic liver disease.