Furthermore, through the modulation of inflammatory responses, with reduce expression of TNF-α, IL-6, IL-1, and IL-8 of monocytes, f TNF-α, IL-6, IL-1, and IL-8 of monocytes, Vitamina D may influence the pathophysiology of atherosclerosis [48,49]. The gene discussed is CXCL8; the disease is atherosclerosis.