We found that the mean sFlt-1/PlGF ratio was significantly higher among women who developed preeclampsia compared to women without preeclampsia, when using sFlt-1/PlGF ratio cut-off value >38 (sensitivity 58.6%; specificity 91.1%; PPV 63%; NPV 89.3% and AUC 74.8%,p<0.001; 95% CI 63.3–86.3). This evidence concerns the gene PGF and preeclampsia.