CCL27 and rheumatoid arthritis: Although ILC depletion and recovery has been reported in rheumatoid arthritis (Rauber et al., 2017), inflammation-driven ILC-depletion is not necessarily reversible, as ILCs appear permanently depleted after HIV-1 infection, possibly by the high levels of common γ-chain cytokines that are present during acute infection (Wang et al., 2020).