Given the decline in ILC abundance with age (Figures 2A and 3A, and Table 2), and the inverse relationship between ILC abundance and disease severity in adults (Figure 3C, and Tables 3 and 4), it was hypothesized that children as a group have less severe COVID-19 because ILC abundance is higher at younger ages, and that pediatric cases with symptomatic SARS-CoV-2 infection, or with MIS-C, are accompanied by significantly lower numbers of ILCs. This evidence concerns the gene CCL27 and COVID-19.