In addition, CaMKII becomes increasingly active in several cardiac pathologies (Anderson et al., 2011; Hegyi et al., 2019; Vincent et al., 2014) and an increased CaMKII activity was associated with enhanced arrhythmogenicity, including atrial fibrillation (Chelu et al., 2009; Yan et al., 2018). Here, CAMK2G is linked to atrial fibrillation.