CMTM5 is a member of the CMTM protein family (Han et al., 2003) that has been associated with regulating tumor immunity (Burr et al., 2017; Mezzadra et al., 2017; Shao et al., 2007; Xiao et al., 2015; Yuan et al., 2020), including CMTM5 itself. Here, CMTM5 is linked to neoplasm.