Moreover, further ROC curve exhibited that JKAP could work as a susceptibility biomarker in differentiating AIS patients from controls (area under curve [AUC]: 0.810, 95% confidence interval [CI]: 0.732–0.888) with the best cutoff value of 59.80 pg/ml (Figure 1B). The gene discussed is DUSP22; the disease is androgen insensitivity syndrome.