Recently, these channels have also been reported to be important for various diseases, yet data on the role of TRPML1 (also known as MCOLN1) in cancer is just emerging (Chao et al., 2017; Grimm et al., 2014; Kiselyov et al., 2012; Müller et al., 2021; Nguyen et al., 2017; Sakurai et al., 2015; Santoni et al., 2020; Shen et al., 2012). This evidence concerns the gene MCOLN1 and cancer.