In mucolipidosis type IV patients, macroautophagy has been reported to be disturbed, as indicated by accumulation of autophagic markers LC3 and p62 (Curcio-Morelli et al., 2010; Di Paola et al., 2018; Vergarajauregui et al., 2008). Here, MAP1LC3A is linked to mucolipidosis type IV.