Yoda1 sensitizes cancer cells including MDA-MB-231 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis (Hope et al., 2019), but in other cell types, Yoda1 alone does not reduce cell viability (Blythe et al., 2019; Chubinskiy-Nadezhdin et al., 2019; Davies et al., 2019). This evidence concerns the gene TNFSF10 and cancer.