There is still a lack of controlled studies investigating the daily use of emollients in infants and toddlers with visibly dry skin who already have eczema or who have genodermatosis with skin barrier disorders associated with IgE-mediated sensitization (especially ichthyosis vulgaris, Netherton syndrome) – also with the aim of preventing further eczema and allergies. Here, IGHE is linked to Netherton syndrome.