Among this early diagnosis panel, four proteins were previously reported to be associated with uveitis, including Neutrophil collagenase (MMP8), Haptoglobin (HPT), Alpha-1-acid glycoprotein (AN1G), and Complement component C9 (C9), Matrix metalloproteinases (MMPs) constitute a family of zinc-dependent endopeptidases that function to maintain and remodel tissue architecture. The gene discussed is MRS2; the disease is uveitis.