We explored TCGA, GTEx, and GEO databases in this study to perform a pan-cancer analysis of FUBP1 to investigate its gene expression level and relationship with pathological staging and prognosis, genetic alteration, DNA methylation, protein phosphorylation, and immune infiltration to uncover the potential molecular mechanism of FUBP1 in different tissues as well as its significance for clinical prognosis. Here, FUBP1 is linked to cancer.