Owing to a lack of data for normal tissue in The Cancer Genome Atlas (TCGA) database (www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga/), we used the GEPIA database (http://gepia.cancer-pku.cn/) to explore IQGAP3 expression in human cancer types. This evidence concerns the gene IQGAP3 and cancer.