IQGAP3 expression was not only related to the tumor stage of ACC, BRCA, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, ovarian serous cystadenocarcinoma (OV), PAAD, and THCA, but also correlated with lymph node metastasis in BLCA, BRCA, CESC, CHOL, COAD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, MESC, PAAD, PRAD, READ, STAD, and THCA. The gene discussed is IQGAP3; the disease is adrenal cortex carcinoma.