Hallmarks of EMT and the “hypoxia” pathway enriched in the high-risk group promote tumor development and metastasis, and “G2M checkpoint”-related gene overexpression and deficiency of KRAS inhibition-related genes promote abnormal cell division in different tumors (Mittal, 2018; Shirazi et al., 2020; Smith et al., 2020). This evidence concerns the gene KRAS and neoplasm.