used 12 exome-wide microbial quantitative trait loci (mbQTL) analyses, identified variants in several genes, including Myelin gene regulatory factor (MYRF), SEC16 homolog A (SEC16A), Interleukin 17 receptor E-like (IL17REL), and WD repeat domain 78 (WDR78), which were related with IBD. The gene discussed is MYRF; the disease is inflammatory bowel disease.