In the ctDNA from the second plasma sampling at the time of disease progression in the primary stomach tumor (week 26), 2 KIT variants were detected, namely, exon 11 c.1673_1687del (AF = 3.1%) and exon 17 c.2485G>C (AF = 3.4%), the latter of which was a new variant not previously detected in the tumor. This evidence concerns the gene KIT and neoplasm.