NECTIN2 and Alzheimer disease: The PVRL2 rs6859 AG, AA, and AG/AA genotypes were significantly associated with increased MCI-AD progression, compared with GG genotype (AG vs. GG, HR (95%CI) = 2.53 (1.14–5.58), p = .022, FDR (P) = .040; AA vs. GG, HR (95%CI) = 3.12 (1.30–7.83), p = .011, FDR (P) = .030; AG/AA vs. GG, HR (95%CI) = 2.75 (1.32–5.76), p = .007, FDR (P) = .030, Table 3, model 2).