Comorbid T2D alters TB and latent TB infection adipokine levels, with the pro-inflammatory adipokine leptin levels increased, while anti-inflammatory adiponectin levels decreased compared to those of TB patients without T2D (23), Kumar et al. (2016) found this change to be independent of BMI (23, 31). The gene discussed is ADIPOQ; the disease is type 2 diabetes mellitus.