Based on the StarBASE database and GEPIA database, we can infer that LIMK2 was upregulated in BLCA, CHOL, LIHC, LUSC, STAD, and UCEC and downregulated in COAD, KICH, KIRP, LUAD, and THCA and that LIMK2 may be a key regulatory factor in the above cancers. Here, LIMK2 is linked to cancer.