With increasing values of basic characteristics in the original FINDRISC questionnaire and increasing levels of lipid metabolic and obesity-related indicators, including systolic and diastolic blood pressure, FBG, 2hPG, HbA1c, fasting serum insulin level, TC, and TG, the FINDRISC values increased significantly. This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.