As recently reported, ADA inhibited the growth of ovarian cancer ES-2 cells by targeting glutamicoxaloacetic transaminase 1 (GOT1) and induced apoptosis by regulating the Bax/Bcl-2 ratio in hepatoma cells (Ocker et al., 2004; Wang et al., 2019). The gene discussed is BCL2; the disease is hepatocellular carcinoma.