Further, high-resolution copy-number analysis revealed genetic alterations in CTCs in genes related to cancer cell dormancy, such as AKT2, PTEN and CADM2, genes associated with invasion and metastasis, such as ANGPTL4, BSG, miR-373 and LTBP4 and anti-apoptosis genes, such as miR-24, LTBP4, TFF3, NUMBL and miR-181 [114]. This evidence concerns the gene LTBP4 and cancer.