reported that there was a EMT molecular network in SHH MB cancer stem cells, which sustained the mesenchymal phenotype of the cells.67 In the present study, we demonstrated the involvement of EMT in Kir2.1-promoted invasion and metastasis of non-WNT/SHH MB cells, where manipulating Kir2.1 expression accordingly changed the expression of E-cadherin, Vimentin, and Slug. The gene discussed is CDH1; the disease is cancer.