However, at present, the antidiabetic drugs for the treatment of AD mainly focus on GLP-1R agonists (liraglutide, exenatide), thiazolidinediones (pioglitazone, rosiglitazone), DPP-4 inhibitors (sitagliptin, vildagliptin), and so on, while there are limited studies of α-glucosidase inhibitors in the treatment of AD, and these findings remain to be further estimated. This evidence concerns the gene GLP1R and Alzheimer disease.