Areas showed that serum levels of cystatin C had a slightly better discriminative power in prediction of AKI than SCr (AUROC 0.821, 95% confidence interval, 0.752 to 0.891 and AUROC 0.813, 95% confidence interval, 0.736 to 0.890, P < 0.001, respectively). This evidence concerns the gene CST3 and acute kidney injury.