Also in line with our data is a study of 191 high‐risk BCP‐ALL cases, of which 56 harbored IKZF1 alterations [56], showing high CD34 gene expression to associate with detectable MRD levels [54], while Cas9/CRISPR‐mediated depletion of CD34 resulted in reduced growth in liquid culture of IKZF1‐mutated human BCP‐ALL cells [54]. Here, IKZF1 is linked to acute lymphoblastic leukemia.