Collected 147 genes for interaction genes of sarcopenia versus proliferating myoblasts and 54 genes for interaction genes of sarcopenia versus differentiated myotubes were compared using R, followed by identification of 15 common DEGs (LXN, CIB2, PEA15, KANK2, FGD1, NMRK1, PLCB1, SEMA4G, ADARB1, UPF3A, CSTB, COL3A1, CD99, ETV3 and FJX1) (S1 Table). The gene discussed is PLCB1; the disease is sarcopenia.