To further evaluate the differences between class II and more active nephritis, we combined patients with class III, IV, V. (Fig 2). MCP-1 was significantly higher in the combined class (MCP1: Combined, 9.7 (4.9, 23.8) versus Class II 2.4 (1.7, 6.9), p = 0.017). This evidence concerns the gene CCL2 and nephritis.