For example, centrosomal protein 131 (CEP131) was recognized as a novel substrate of PLK4 that facilitated centrosome amplification and colon cancer development [8]; overexpression of centrosomal protein 70 (CEP70) stimulated the growth of pancreatic cancer cells by inducing abnormal centrosomes and disorganized microtubules [9]. The gene discussed is CEP70; the disease is familial pancreatic carcinoma.