In terms of allelic comparisons, the CC allele of the estrogen receptor gene polymorphism was not associated with susceptibility to PCOS with OR = 1.36 (95%) CI = (0.77 to 2.375), RR = 1.01 (0.909 to 1.302), p < 0.35. This evidence concerns the gene ESR1 and polycystic ovary syndrome.