Similarly, SBP (>120 mmHg), TG (>150 mg/dl), poor sleep (>5 scores), higher CRP (>3 mg/L) and lower femoral neck BMD (<0.7 g/cm2) and BMD at lumbar spine (<0.8 g/cm2) were independent risk factors for the risk of osteopenia. The gene discussed is CRP; the disease is Osteopenia.