Mood states: POMS (anxiety (+), depression (+), anger (+), confusion (+), vigor (/), fatigue (/));Cardiovascular disease risk biomarkers: BNP (+), ET-1 (+), AGT (/), ANG II (/), AT1 (/), AT2 (+);Inflammatory cytokine: IL-6 (+), TNF-α (/), HCRP (/);Oxidative stress: Serum MDA (+), T-SOD (+). This evidence concerns the gene NPPB and depressive disorder.