CD4 and type 1 diabetes mellitus: According to Fisher et al., in patients with type 1 diabetes, different doses of vitamin D caused a higher proportion of T regulatory cells in comparison with controls [+6.4% (DS 0.8%) of CD4+CD25+CD127, +4.55% ± 1.5% of CD4+CD25+Foxp3+, +22.2 ± 47.2% of CD4+CD25hi FoxP3+CD127low in CD4+ cells, respectively].