TFE3 and glioblastoma: We then examined the effect of TFE3 on cell proliferation by MTS (3-(4,5-Dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay and found that the proliferation of glioblastoma cell lines, A172 and LN229, also decreased after knocking down TFE3 (Figure 5c).