Similarly, circ0046701 and circHIPK3 fostered proliferative and invasive features of glioma cells by targeting the axes miR-142-3p/ITGB8 (integrin subunit beta 8) and miR-654/IGF2BP3 (insulin-like growth factor 2 mRNA-binding protein 3), respectively [160,161,162]. Here, ITGB8 is linked to central nervous system cancer.