Interestingly, ZNF451-BAG2 fusion transcript encoded a smaller 19.6 kDa protein (ΔBAG2) that impaired the clearance of the phosphorylated forms of the TAU protein (pTAU), as consequence of the impaired binding to heat shock cognate 70 (HSC70), and inhibited retinoic acid-induced differentiation of neuroblastoma (Figure 3C) [191]. This evidence concerns the gene ZNF451 and neuroblastoma.