Serum DKK-1 levels could be further evaluated in 11 HpSC-HCC and 36 MH-HCC cases by enzyme-linked immunosorbent assay (ELISA) and were found to be higher in HpSC-HCC samples compared to MH-HCC samples (p = 0.003, Figure 1E). The gene discussed is DKK1; the disease is hepatocellular carcinoma.