Relevant articles were searched as follows: (“Berbamine” OR “Berberis amurensis” AND “*”), where “*” stands for: (i) “cancer” OR “tumor” OR “tumour”; (ii) “JAK/STAT signaling” OR “JAK/STAT”; (iii) “TGF/SMAD Pathway” OR “TGF/SMAD” (iv) “Ca2+/calmodulin-dependent protein kinase II” OR “CAMKII”; (v) “Autophagy” OR “autophagy inhibitor”; (vi) “Nontechnology” OR “Nontechnological Approaches”; (vii) “Delivery”; (viii) cancer chemopreventive OR chemotherapy; (ix) “microRNA” OR “miR” OR “miRNA”. The gene discussed is CAMK2G; the disease is neoplasm.