RNA-binding motif protein 20 (RBM20), which is an important pathogenic gene of myocardial disease, is dependent on TTNcircRNAs and targets multiple key cardiac genes, such as calcium/calmodulin-dependent kinase II (CAMK2D), while also being dependent on titin (TTN) circRNAs [33]. This evidence concerns the gene RBM20 and myocardial disorder.