IGF1 and myocardial infarction: During post-myocardial infarction (MI) inflammation, miR-1 suppresses the anti-apoptotic genes by targeting heat shock proteins (HSPs) such as Hsp 60, Hsp-70, insulin-like growth factor 1 (IGF-1), and B-cell lymphoma 2 (BCL-2), all of which act as sensors to extracellular damage-associated molecular patterns (DAMPs) released from the injured cardiac tissue [75,76,77].