However, corylin inhibited the mRNA expression and protein levels of Ifnγ, Tnf-α, Il-6, Il-1β, Nlrp3, Asc, Pannexin, and Pro-caspase 1 (Figure 6C–F) in the tumor tissues of AOM/DSS-induced CAC mice. This evidence concerns the gene NLRP3 and infectious otitis media.