CXCR4 and neoplasm: Inhibited CXCL12-CXCR4 enhancement of ARHGAP10 expression, thereby suppressing EOC cell invasion [32]. In combination with taxol, significantly reduced the proliferation of human and mouse EOC cells [96]. CXCR4 inhibition increased T cell-mediated anti-tumor immune response and slowed EOC progression [98].