These genetic disorders are prone to be modeled on D. melanogaster, since the fruit fly genome contains the hu li tai shao (hts) ortholog for ADD1 (adducin-α), ADD2 (adducin-β) and ADD3, and Gcn5 acetyltransferase (Gcn5) paralog for KAT2A and KAT2B. This evidence concerns the gene KAT2B and hereditary disease.