VEGFA and cancer: Disrupted pathways included KEGG 05230 (Central carbon metabolism in cancer), KEGG 04370 (VEGF signaling pathway), KEGG 04664 (Fc epsilon RI signaling pathway), KEGG 05205 (Proteoglycans in cancer) or KEGG 05204 (Chemical carcinogenesis-DNA adducts), indicating a significantly increased risk of initiation and/or acceleration of carcinogenesis.